Rebirth deals with the devil

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  1. Devil Room (Item Pool) - Binding of Isaac: Rebirth Wiki
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  3. Devil Room
  4. Devil Room (Afterbirth+ Item Pool)

Greed Mode. Guppy's Head. Spawns blue flies to damage enemies. Guppy's Paw.


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  • Devil Room | The Binding of Isaac: Rebirth Wiki | FANDOM powered by Wikia.

Removes one red heart container in exchange for gaining 3 Soul Hearts. Mega Blast. Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active. The Book of Belial. Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or increases the chance by The Book of Sin. Spawns a random pickup , pill , card , or trinket. The Necronomicon.


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  3. Devil Room (Afterbirth Item Pool)!
  4. Devil Room (Item Pool).
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  6. We Need to Go Deeper! Creates a trapdoor to go to the next floor. If used in The Womb , it will create a trapdoor to Sheol , even if the player hasn't unlocked it. Satanic Bible. Upon activation, Isaac gains a black heart. Adds one soul heart and allows the breaking of rocks and damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.

    Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies. Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.

    Black Powder. Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it. Brother Bobby. Cambion Conception. After taking damage a certain amount of times, a permanent demonic familiar spawns. Ceremonial Robes. Adds 3 black hearts and increases Damage by 1.

    Contract From Below. Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action such as using a blood donation machine , but reduces the chance for any pickups to spawn at all. Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart , one hostile Spider or one friendly blue spider. Increases Damage by 1 and adds a chance to shoot fear tears.

    Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again. Empty Vessel.

    Devil Room (Item Pool) - Binding of Isaac: Rebirth Wiki

    While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any red hearts, these benefits will disappear. Spawns a familiar that follows Isaac around and fires spectral tears. Has a chance of spawning a soul heart or black heart when taking damage.

    Enemies have a chance to drop a Half Red Heart after being killed. Guppy's Collar. Guppy's Hair Ball. Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies.

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    Guppy's Tail. Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups. Headless Baby. Familiar that follows Isaac, leaving blood creep on the ground. Missing Page 2. Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.

    Multidimensional Baby. Bomb Bum. Greed Mode. The Book of Belial. Guarantees a Devil Room or Angel Room will be open after beating a boss while holding it, or increases the chance by The Book of Sin. Spawns a random pickup , pill , card , or trinket. Guppy's Head. Spawns blue flies to damage enemies. Guppy's Paw. Removes one red heart container in exchange for gaining 3 Soul Hearts.

    The Necronomicon. We Need to Go Deeper! Creates a trapdoor to go to the next floor. If used in The Womb , it will create a trapdoor to Sheol , even if the player hasn't unlocked it. Satanic Bible. Upon activation, Isaac gains a black heart. Adds one soul heart and allows the breaking of rocks and damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.

    Brother Bobby. Ceremonial Robes. Adds 3 black hearts and increases Damage by 1. Contract From Below.

    Devil Room

    Doubles the number of pickups and chests spawned after clearing a room or performing some other triggering action such as using a blood donation machine , but reduces the chance for any pickups to spawn at all. Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart , one hostile Spider or one friendly blue spider. Increases Damage by 1 and adds a chance to shoot fear tears. Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room.

    New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again. Spawns a familiar that follows Isaac around and fires spectral tears. Has a chance of spawning a soul heart or black heart when taking damage.

    Devil Room (Afterbirth+ Item Pool)

    Enemies have a chance to drop a Half Red Heart after being killed. Guppy's Collar. Guppy's Hair Ball. Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies. Guppy's Tail. Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups. Headless Baby. Familiar that follows Isaac, leaving blood creep on the ground. Missing Page 2. Gives 1 black heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.

    Increases damage and increases the chance for a Devil or Angel Room to appear. Sacrificial Dagger.